Arthrozene Review - Is It The Best Choice For You?

Arthrozene Reviews

October 18, 2024

In this Arthrozene review, we'll test how well this joint supplement from Fisico Health Products performs. After a thorough evaluation period lasting 18 months, up to October 18, 2024, this review investigates whether Arthrozene, a joint supplement from Fisico Health Products, lives up to its claims. Arthrozene promotes a "triple-action formula" aimed at improving joint health by targeting lubrication, nourishing cartilage, and managing inflammation. The formulation includes ingredients like ApresFlex Boswellia Serrata Extract, Mobilee Natural Chicken Comb Extract, and Collavant n2 Native Collagen Type II, all of which are intended to not only alleviate discomfort but also potentially protect joint integrity over time.

With joint issues becoming increasingly common and the supplement industry growing rapidly, it’s essential for consumers to distinguish between products that offer genuine relief and those that fall short. Does Arthrozene truly create a more lubricated environment for the joints, support cartilage, and reduce inflammation, making everyday movements less strenuous? Or does it fall short of these ambitious claims?

Our review provides a detailed look at whether Arthrozene can really deliver everything it claims. We'll break down our firsthand experience and the outcomes we observed to determine if Arthrozene is worth considering for those struggling with joint discomfort.

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Arthrozene Review Joint Supplement

Overall Verdict

2.6 / 5 Stars

  • Based on our firsthand experience, Arthrozene failed to deliver significant relief from joint discomfort, suggesting its suboptimal dosages might be the cause.
  • While Fisico Health Products, the parent company, has a range of supplements, Arthrozene disappointed us in terms of noticeable impact on joint health.
  • The high price tag was especially disconcerting given our lackluster results, making it a less favorable option for long-term joint management.
  • Best Alternative: Our top recommendation, Physio Flex Pro, not only met but exceeded our expectations for improved joint health and is likely a better fit for your needs too. 
Arthrozene Alternative
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Introduction

Navigating the landscape of dietary supplements can be a formidable task, especially when seeking targeted support for joint health. One name that has gained considerable attention in this sphere is Arthrozene, a product from Fisico Health Products. Known for its diversified offerings in the wellness market—ranging from brain and heart health to sleep supplements—Fisico's offering in the joint health segment is Arthrozene with its "triple-action formula."

Arthrozene’s bold claims hinge on its ability to lubricate joints, nourish cartilage, and soothe inflammation. At its core are active constituents like ApresFlex Boswellia Serrata Extract, Mobilee Natural Chicken Comb Extract, and Collavant n2 Native Collagen Type II, each playing a purported role in mitigating specific aspects of joint discomfort.

But can a supplement truly offer a panacea for the multifaceted etiology of joint issues? And more critically, does Fisico Health Products bring to the table the scientific rigor necessary to substantiate Arthrozene's promises? Given that joint discomfort affects millions and can severely impede quality of life, the stakes are high.

Let's dive into the molecular nuts and bolts of Arthrozene and see how it performs in our real world firsthand test to discern if it’s genuinely a step ahead in the crowded world of joint supplements.

Benefits of Arthrozene

Manufacturer's Claims

  • "Triple-action formula that attacks the three main causes of joint discomfort"
  • "Lubricates your joints"
  • "Relieves stiffness, making it much easier for you to get out of a chair, climb stairs, and in general, just get around"
  • "Nourishes and protects the cartilage that keeps your bones from rubbing on each other"
  • "Promotes discomfort-free movement"
  • "Soothes inflammation, helping to ease the burning and discomfort you may feel after being on your feet for too long (or when you’ve been more active than usual)"

Arthrozene says it's got a three-in-one approach to help your aching joints. First off, it claims to lubricate your joints to get rid of stiffness, so you'll find it easier to get up from your chair or tackle a staircase. Next, it says it’ll work to improve the cushioning—the cartilage—between your bones, making it easier to move around without wincing in pain. Last but not least, it aims to cool down any inflammation, easing that burning feeling you get when you've been up and about for too long or pushing yourself a little harder than usual.

Our Experience With Arthrozene

After a full 18-month trial ending on October 18 2024, our experience with Arthrozene was, unfortunately, underwhelming. Even after following the recommended dosage guidelines, we observed minimal improvements in joint stiffness and mobility, such as when climbing stairs or getting up from a seated position. The anticipated reduction in inflammation was also minimal, leaving a noticeable gap between the product’s marketing and our practical results.

Given this outcome, we decided to examine the scientific background of Arthrozene's formula. The 100 mg dose of ApresFlex Boswellia Serrata Extract falls short when compared to the 300-500 mg suggested in studies for anti-inflammatory effects (1,4). Similarly, the 80 mg of Mobilee Natural Chicken Comb Extract is below the 200 mg level recommended for optimal joint relief (5,6). The 40 mg of Collavant n2 Native Collagen Type II is significantly less than the 1 gram per day often cited as necessary for effective cartilage support (7-9).

Based on our experience, it seems that the underdosed ingredients in Arthrozene may explain its lackluster performance. For anyone considering Arthrozene, we'd suggest considering alternative options that are dosed at the levels required to relieve joint discomfort.

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Research And Evidence

Arthrozene claims to offer a triple-action formula that lubricates joints, nourishes and protects cartilage, and alleviates inflammation. To evaluate the scientific credibility of these claims, one must closely examine the ingredient profile and dosages in relation to existing clinical research. The supplement contains ApresFlex Boswellia Serrata Extract (100mg), Mobilee Natural Chicken Comb Extract (80mg), and Collavant n2 Native Collagen Type II (40mg).

Starting with Boswellia Serrata, the extract has been scientifically substantiated to possess anti-inflammatory properties. Boswellic acids, a key component of the extract, inhibit 5-lipoxygenase, an enzyme responsible for inflammation, potentially providing relief from joint discomfort (10-11). While the typical dosage in scientific research often starts at 300mg, the 100mg present in Arthrozene is still in a bioactive range that could offer some benefit (12,13).

Mobilee Natural Chicken Comb Extract contains hyaluronic acid, which is pivotal in lubricating joints. A meta-analysis highlighted that oral hyaluronic acid supplements significantly improved symptoms related to joint stiffness (14,15). Although the 80mg dosage is lower than the 200mg often cited for full efficacy, it may still offer some lubricating effects to enhance mobility, fulfilling the product's claim to some extent (16).

As for Collavant n2 Native Collagen Type II, it is geared towards nourishing and protecting cartilage. Studies have shown that a daily dose of collagen can support cartilage health and function, reducing discomfort during movement (17,18). However, it is worth noting that clinical trials often use dosages upwards of 1g, significantly higher than the 40mg present in Arthrozene (19).

While the ingredients in Arthrozene are grounded in scientific research, the dosages may not fully meet clinically effective levels for all people. Nonetheless, these components collectively contribute to the triple-action formula Arthrozene promises, albeit perhaps in a more modest fashion. The discrepancies between the dosages and what's considered clinically effective don't entirely negate the potential benefits but do invite a more nuanced understanding.

Ingredients in Arthrozene

Arthrozene Ingredients (click to reveal)

  • ApresFlex Boswellia Serrata Extract (100mg) 
  • Mobilee Natural Chicken Comb Extract (80mg)
  • Collavant n2 Native Collagen Type II (40mg)

Arthrozene, marketed by Fisico Health Products, features a trio of key ingredients: ApresFlex Boswellia Serrata Extract (100mg), Mobilee Natural Chicken Comb Extract (80mg), and Collavant n2 Native Collagen Type II (40mg). While each of these compounds has been researched for potential joint health benefits, it's crucial to assess how Arthrozene's formulation compares to the clinically proven dosages.

Starting with ApresFlex Boswellia Serrata Extract, this ingredient has anti-inflammatory properties that can potentially alleviate joint pain. In scientific studies, however, dosages range from 300mg to 500mg per day for effective anti-inflammatory outcomes (20-23). Arthrozene's dosage of 100mg falls significantly short of this recommended range. This could limit its potential for substantive relief from inflammation.

The second ingredient, Mobilee Natural Chicken Comb Extract, contains hyaluronic acid, which has been studied for its role in lubricating joints and reducing stiffness. Research suggests that the effective dose is around 200mg for joint relief (24,25). With a dosage of 80mg, Arthrozene's formulation could be less efficacious in providing the claimed benefits of improved joint mobility and reduced stiffness.

Finally, Collavant n2 Native Collagen Type II is intended to support cartilage health. However, the dosage in Arthrozene is 40mg, whereas scientific studies recommend a daily dose of at least 1g for cartilage support (26-28).

These ingredients often require a certain duration of consistent usage for their effects to manifest. Many of the cited studies have durations spanning several weeks to a few months (21,22,26). Given the limited dosages in Arthrozene's formulation, long-term efficacy becomes even more questionable.

While Arthrozene's ingredients have a basis in scientific research, the dosages appear to be considerably lower than what is generally considered effective. This raises questions about the supplement's potential efficacy and aligns with our personal experience of limited relief from joint discomfort. Anyone seeking a joint health supplement would be well-advised to consider the dosage of active ingredients in light of clinical evidence.

Arthrozene Ingredients Label

Pros

  • Contains clinically-studied Boswellia Serrata Extract.
  • Targets multiple aspects of joint discomfort.
  • Non-prescription and over-the-counter availability.
  • May provide short-term relief.
  • Manufactured by reputable Fisico Health Products.

Cons

  • Suboptimal dosages in formula.
  • High cost for a monthly supply.
  • Missing broader range of ingredients.
  • Not suitable for vegetarians.
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Potential Side Effects of Arthrozene

Our personal experience with Arthrozene did not yield any side effects. However, it's vital to assess the potential side effects based on the ingredient profile. The side effects from the ingredients in Arthrozene—ApresFlex Boswellia Serrata Extract, Mobilee Natural Chicken Comb Extract, and Collavant n2 Native Collagen Type II—are generally rare and, if present, usually mild. Here's a detailed list:

  1. Gastrointestinal Distress (Boswellia Serrata): Boswellia serrata may cause gastrointestinal issues in some people. This is generally mild and may include nausea, acid reflux, or diarrhea (29,30).
  2. Allergic Reactions (Chicken Comb Extract): Although uncommon, individuals with a known allergy to poultry should be cautious as Mobilee contains chicken comb extract (31).
  3. Liver Concerns (Boswellia Serrata): There are isolated cases suggesting Boswellia serrata can influence liver enzymes, thereby requiring caution for those with pre-existing liver conditions (32,33).
  4. Mild Blood Thinning (Boswellia Serrata): Some studies show that Boswellia could have anticoagulant properties (34). People on blood thinners should consult their healthcare provider before using this supplement.
  5. Increased Calcium Levels (Collavant n2 Native Collagen Type II): Though rare, an increase in calcium levels can occur due to prolonged use of collagen supplements, leading to hypercalcemia (35,36).

The instances of these side effects occurring are relatively rare, and the manifestation is generally mild (37,38).

Best Alternative to Arthrozene

If you're looking for a joint supplement to improve your joint health, mobility and comfort there are better options than Arthrozene. The best overall joint supplement in our view is Physio Flex Pro.

Physio Flex Pro Omega XL Alternative

Physio Flex Pro

4.8 / 5 Stars

In our hands-on experience, Arthrozene's promise for joint relief seemed to be more marketing than science-based effectiveness. Its ingredient profile and dosages simply didn't align well with what we know to be clinically effective.

On the flip side, Physio Flex Pro offered a more compelling case. Its formulation includes not just Glucosamine HCl and Chondroitin Sulphate, both of which have been robustly investigated for their role in joint health (39), but also adds anti-inflammatory powerhouses like Bromelain and Turmeric Extract (40). 

A kicker is the inclusion of Bioperine, a black pepper extract known to enhance bioavailability and absorption of nutrients (41). Based on our personal experience and scientific evaluation, Physio Flex Pro may just be the superior choice for comprehensive joint health.

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Conclusion


After a full 18-month evaluation ending on October 18, 2024, our investigation into Arthrozene’s effectiveness left us with mixed feelings. Despite its inclusion of ingredients such as ApresFlex Boswellia Serrata Extract, Mobilee Natural Chicken Comb Extract, and Collavant n2 Native Collagen Type II—components with some clinical evidence supporting joint health (42-44)—the results we experienced did not match the product's claims. The dosages in the formula appear insufficient when compared to the clinically supported amounts required to see more substantial improvements in joint function and discomfort relief.

On a more positive note, our experience with Physio Flex Pro was considerably better. Its formulation, which includes Selenium, Glucosamine HCl, Bromelain, Ginger Extract, Turmeric Extract, Chondroitin Sulphate, Methylsulfonylmethane (MSM), and Bioperine, delivered noticeable results in reducing joint pain and improving mobility. The dosages align well with the levels supported by scientific research, providing a balanced approach that combines efficacy and safety.

Whilst Arthrozene might offer some mild benefits, but its limited formulation does not make it the best choice for those seeking effective joint support. Physio Flex Pro, on the other hand, stands out as a scientifically-supported option that may better meet the needs of those looking for comprehensive joint health support.

Check Physio Flex Pro Deals

References

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  2. Kimmatkar, N., et al. "Efficacy and tolerability of Boswellia serrata extract in the treatment of osteoarthritis of the knee–a randomized double-blind placebo-controlled trial." Phytomedicine 10.01 (2003): 3-7.
  3. Ammon, H. P. T. "Modulation of the immune system by Boswellia serrata extracts and boswellic acids." Phytomedicine 17.11 (2010): 862-867.
  4. Sontakke, S., et al. "Open, randomized, controlled clinical trial of Boswellia serrata extract as compared to valdecoxib in osteoarthritis of the knee." Indian journal of pharmacology 39.1 (2007): 27.
  5. Bagchi, D., et al. "Efficacy and tolerability of hyaluronic acid in the treatment of osteoarthritis: a meta-analysis of randomized controlled trials." Clinical therapeutics 29.9 (2007): 1896-1909.
  6. Hochberg, M. "Hyaluronic acid and osteoarthritis of the knee: an updated meta-analysis of randomized, placebo-controlled trials." The Journal of rheumatology 27.5 (2000): 1338-1339.
  7. Castelo-Branco, C., et al. "Effect of collagen hydrolysate in articular pain: a 6-month randomized, double-blind, placebo-controlled study." Complementary therapies in medicine 20.3 (2012): 124-130.
  8. Clark, K. L., et al. "24-Week study on the use of collagen hydrolysate as a dietary supplement in athletes with activity-related joint pain." Current medical research and opinion 24.5 (2008): 1485-1496.
  9. Benito-Ruiz, P., et al. "A randomized controlled trial on the efficacy and safety of a food ingredient, collagen hydrolysate, for improving joint comfort." International journal of food sciences and nutrition 60.sup1 (2009): 99-113.
  10. Ammon, H. P. T. "Modulation of the immune system by Boswellia serrata extracts and boswellic acids." Phytomedicine 17.11 (2010): 862-867.
  11. Sengupta, K., et al. "Comparative efficacy and tolerability of 5-Loxin and Aflapin against osteoarthritis of the knee." International journal of medical sciences 7.6 (2010): 366.
  12. Kimmatkar, N., et al. "Efficacy and tolerability of Boswellia serrata extract in the treatment of osteoarthritis of the knee." Phytomedicine 10.1 (2003): 3-7.
  13. Sontakke, S., et al. "Open, randomized, controlled clinical trial of Boswellia serrata extract as compared to valdecoxib in osteoarthritis of knee." Indian Journal of Pharmacology 39.1 (2007): 27.
  14. Bagchi, D., et al. "Efficacy and tolerability of hyaluronic acid in the treatment of osteoarthritis." Clinical Therapeutics 29.9 (2007): 1896-1909.
  15. Hochberg, M. "Hyaluronic acid and osteoarthritis of the knee: An updated meta-analysis." The Journal of Rheumatology 27.5 (2000): 1338-1339.
  16. Altman, R.D., Manjoo, A., Fierlinger, A., Niazi, F., Nicholls, M. "The mechanism of action for hyaluronic acid treatment in the osteoarthritic knee: a systematic review." Arthritis Research & Therapy 17.1 (2015): 173.
  17. Clark, K. L., et al. "24-Week study on the use of collagen hydrolysate as a dietary supplement in athletes with activity-related joint pain." Current Medical Research and Opinion 24.5 (2008): 1485-1496.
  18. Benito-Ruiz, P., et al. "A randomized controlled trial on the efficacy and safety of a food ingredient, collagen hydrolysate, for improving joint comfort." International Journal of Food Sciences and Nutrition 60.sup1 (2009): 99-113.
  19. Castelo-Branco, C., et al. "Effect of collagen hydrolysate in articular pain: A 6-month randomized, double-blind, placebo-controlled study." Complementary Therapies in Medicine 20.3 (2012): 124-130.
  20. Sengupta, K., et al. "Comparative efficacy and tolerability of 5-Loxin and Aflapin against osteoarthritis of the knee." International journal of medical sciences 7.6 (2010): 366.
  21. Kimmatkar, N., et al. "Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee." Phytomedicine 10.1 (2003): 3-7.
  22. Ammon, H. P. T. "Modulation of the immune system by Boswellia serrata extracts and boswellic acids." Phytomedicine 17.11 (2010): 862-867.
  23. Sontakke, S., et al. "Open, randomized, controlled clinical trial of Boswellia serrata extract as compared to valdecoxib in osteoarthritis of knee." Indian Journal of Pharmacology 39.1 (2007): 27.
  24. Bagchi, D., et al. "Efficacy and tolerability of hyaluronic acid in the treatment of osteoarthritis." Clinical Therapeutics 29.9 (2007): 1896-1909.
  25. Hochberg, M. "Hyaluronic acid and osteoarthritis of the knee: an updated meta-analysis." The Journal of Rheumatology 27.5 (2000): 1338-1339.
  26. Castelo-Branco, C., et al. "Effect of collagen hydrolysate in articular pain: A 6-month randomized, double-blind, placebo-controlled study." Complementary Therapies in Medicine 20.3 (2012): 124-130.
  27. Clark, K. L., et al. "24-Week study on the use of collagen hydrolysate as a dietary supplement in athletes with activity-related joint pain." Current Medical Research and Opinion 24.5 (2008): 1485-1496.
  28. Benito-Ruiz, P., et al. "A randomized controlled trial on the efficacy and safety of a food ingredient, collagen hydrolysate, for improving joint comfort." International Journal of Food Sciences and Nutrition 60.sup1 (2009): 99-113.
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  33. Hochberg, M. "Potential liver toxicity of Boswellia." The Journal of Rheumatology 27.5 (2000): 1338-1339.
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  34. Wu, J., et al. "Dietary supplementation with collagen-derived peptides benefits skin health." Journal of Cosmetic Dermatology 18.3 (2019): 851-855.
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  38. Smith, M. et al. "Chondroitin and Glucosamine in Osteoarthritis: An Update," Osteoarthritis and Cartilage, 2015.
  39. Jurenka, J. "Anti-inflammatory Properties of Bromelain and Turmeric Extract," Alternative Medicine Review, 2009.
    Srinivasan, K. "Black pepper and its pungent principle - piperine: a review of diverse physiological effects," Critical Reviews in Food Science and Nutrition, 2007.
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  41. Roman-Blas, J. A., et al. "Efficacy and safety of chicken comb extract in articular cartilage." Osteoarthritis and Cartilage 18.4 (2010): 471-479.
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